Major epilepsy study offers much-needed answers on 3 lifesaving seizure drugs – Eurekalert

Excerpt:

The study found that the three drugs – intravenous levetiracetam, fosphenytoin, and valproate – were all about equally effective at stopping the potentially deadly seizures when the default choice, benzodiazepines, proved unable to do so. The results were so clear that the shocked researchers stopped their trial early.

“When we planned the study, we didn’t even know if these drugs work 10%, 25% or 50% of the time,” said investigator Jaideep Kapur, MBBS, PhD, the head of the University of Virginia Brain Institute. “So the big, big takeaway is that each of these drugs works about 45 percent of the time. And this is an important finding because it tells us patients can get better. They don’t have to be placed on a on a ventilator [breathing machine].”

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